A peracetylated α-D-mannose ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper-free click chemistry, forming stable 1,2,3-triazole linkages. The sugar hydroxyls are acetate-protected to increase lipophilicity for cell membrane permeability. This compound provides an α-D-mannose building block for glycoconjugate synthesis and the construction of probes for mannose-recognizing receptors and lectins, including the mannose receptor (CD206) and DC-SIGN, with relevance to immune-targeting and pathogen-recognition research.