Mannose-6-phosphonate (M6Pn) ligands are less sensitive to phosphatase degradation than natural Mannose-6-phosphate (M6P) ligands and may offer improved in vivo stability for LYTACs therapeutic applications. The ligand is equipped with a clickable azide-functionalized discrete triethylene glycol spacer.
Other Names:
M6Pn-PEG3-N3;
M6Pn-PEG3-Azide;
α-Man-6-phosphonate-PEG3-N3;
2-[2-(2-Azidoethoxy)ethoxy]ethyl α-D-mannose-6-phosphonate;
(8-Azido-3,6-dioxaoctyl) α-D-mannose-6-phosphonate
