Mannose-6-phosphonate Ligands

Mannose-6-phosphonate (Man6Pn) ligands can be used to target therapeutics such as recombinant enzymes or LYTAC molecules to the lysosome, by exploiting the mannose-6-phosphate receptor (M6PR). Therapeutic payloads can be directly conjugated to Man6P ligands.

We provide Man6Pn ligands with various functional linkers depending on their intended use.