GP900050: MUC1(138-157)-Core 3(150, 151)

GP900050

MUC1(138-157)-Core 3(150, 151)

MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Val138-Gly157; UniProt position 138-157, aa length 20) from the tandem repeat (TR) region of the MUC1 protein. The fragment contains tumor-associated carbohydrate antigen (TACA), Core-3 antigen, O-glycosylation (GlcNAcβ1-3GalNAc) at Ser150 and Thr151. The C-terminus is an amide.

Sequence:

VTSAPDTRPAPGS*T*APPAHG-NH₂
H-Val-Thr-Ser-Ala-Pro-Asp-Thr-Arg-Pro-Ala-Pro-Gly-Ser*-Thr*-Ala-Pro-Pro-Ala-His-Gly-NH₂

where S* = Ser* = GlcNAcβ1-3GalNAcα-O-Ser and T* = Thr* = GlcNAcβ1-3GalNAcα-O-Thr