HBB(2-5-Cys)-Fru(2)

Synthetic N-terminal glycated peptide fragment Val2-Thr5 (without methionine (Met) initiator) of Hemoglobin subunit beta (HBB). See UniProt ID P68871. A non-native C-terminal Cysteine (Cys) has been added for further conjugation providing the sequence with a total of 5 amino acids. Fructose (Fru) is conjugated at the N-terminal Valine. The C-terminus is amide. Glucose reacts non-enzymatically with the N-terminus valine of the beta chain to form a stable ketoamine (fructose) linkage.