GP200102

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Amylin(34-71)-GlcNAc(65)-Synthetic Analogue

Pramlintide is a synthetic analogue of the naturally occurring neuroendocrine hormone Amylin, currently used for type I and type II diabetes patients. Amylin is also known as islet amyloid polypeptide (IAPP). Amylin (UniProt ID P10997) synthetic glycopeptide analogue fragment (Lys34-Tyr71; UniProt position 34-71; aa length 37) with GlcNAcβ at Asn65 position. The C-terminus is an amide.


Sequence:


K(CNTATC)ATQRLANFLVHSSNNFGPILLPPTN*VGSNTY-NH2
H-Lys-(Cys-Asn-Thr-Ala-Thr-Cys)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-leu-Pro-Pro-Thr-Asn*-Val-Gly-Ser-Asn-Thr-Tyr-NH2
Where N* = Asn* = GlcNAcβ-Asn
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Amylin(34-71)-GlcNAc(65)-Synthetic Analogue

Pramlintide is a synthetic analogue of the naturally occurring neuroendocrine hormone Amylin, currently used for type I and type II diabetes patients. Amylin is also known as islet amyloid polypeptide (IAPP). Amylin (UniProt ID P10997) synthetic glycopeptide analogue fragment (Lys34-Tyr71; UniProt position 34-71; aa length 37) with GlcNAcβ at Asn65 position. The C-terminus is an amide.


Sequence:

K(CNTATC)ATQRLANFLVHSSNNFGPILLPPTN*VGSNTY-NH2
H-Lys-(Cys-Asn-Thr-Ala-Thr-Cys)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-leu-Pro-Pro-Thr-Asn*-Val-Gly-Ser-Asn-Thr-Tyr-NH2
Where N* = Asn* = GlcNAcβ-Asn

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  • Other Names

  • Technical Data

    UniProt ID: P10997

    Formula: C185H291N53O59S2

    Molecular Weight: 4265.74

    Purity: >90% (HPLC)

  • Storage & Shipping

    Shipping requirement: Dry Ice

    Storage conditions: -20°C

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