GP200000: RPB1 CTD(1615-1621-Lys)-GlcNAc(1619)

GP200000

RPB1 CTD(1615-1621-Lys)-GlcNAc(1619)

DNA-directed RNA polymerase II (Pol II) subunit RPB1 (UniProt ID P24928) contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr-Ser-Pro-Thr-Ser-Pro-Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process Pol II transcripts.

Sequence:


YSPTS*PSK-NH2
H-Tyr-Ser-Pro-Thr-Ser*-Pro-Ser-Lys-NH2

where S* = Ser* = GlcNAcβ-O-Ser
GP200000: RPB1 CTD(1615-1621-Lys)-GlcNAc(1619)

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Pack Size
Quantity
Price
0.5 mg + $125.00 fee for orders under $500.00 $375.00 USD
$375.00 USD + $125.00 fee for orders under $500.00
1 mg $600.00 USD
$600.00 USD

Technical Data

UniProt ID: P24928

Formula: C46H73N11O18

Molecular Weight: 1068.1

Purity: >90% (HPLC)

Storage & Shipping

Shipping requirement: Dry Ice

Storage conditions: -20°C

Dry ice required. Additional fees may apply. For more details, visit our shipping page.

Other Names

Synthetic RPB1 at C-terminal domain(CTD) glycopeptide

For research and development use only

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GP200000: RPB1 CTD(1615-1621-Lys)-GlcNAc(1619)

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