GP100085

MUC1(138-157)-Tn(144,150,151)

MUC1(138-157)-Tn(144,150,151) Synthetic glycopeptide. Glycosylated Mucin-1 (MUC1) peptide fragment containing amino acid sequence Val138–Gly157 (20 AA in length) from the tandem repeat (TR) region of the MUC1 protein. The fragment contains tumor-associated carbohydrate antigen (TACA), Tn antigen, O-glycosylation (α-GalNAc) at Thr144, 151 and Ser150. The C-terminus is an acid.

Sequence:

VTSAPDT*RPAPGS*T*APPAHG-OH
H-Val-Thr-Ser-Ala-Pro-Asp-Thr*-Arg-Pro-Ala-Pro-Gly-Ser*-Thr*-Ala-Pro-Pro-Ala-His-Gly-OH

where S* = Ser* = GalNAcα-O-Ser, T* = Thr* = GalNAcα-O-Thr