GP000020: FZD8 (541-549)-d8 labelled-STF(541)

GP000020

FZD8 (541-549)-d8 labelled-STF(541)

FZD8(UniProt ID Q9H461) synthetic glycopeptide fragment(Thr541-Ala549; UniProt position 541-549, aa length 9) with Sialyl TF (Neu5Acα2-3Galβ1-3GalNAc) at Thr541. Val542 has been labelled with d8. The C-terminus is carboxylic acid. Antiproliferative factor (APF) is a sialoglycopeptide that contains the transmembrane segment of Frizzled 8, a protein encoded by the FZD8 gene. Highly elevated levels of APF have been associated with interstitial cystitis. Abnormal Akt signaling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells.

Sequence:


T*V(d8)PAAVVVA-OH
H-Thr*-Val-(d8)-Pro-Ala-Ala-Val-Val-Val-Ala-OH

where T* = Thr* = Sialyl TF = STF = Neu5Acα2-3Galβ1-3GalNAcα-O-Thr
GP000020: FZD8 (541-549)-d8 labelled-STF(541)
Pack Size
$500.00 USD
$500.00 USD

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Technical Data

UniProt ID: Q9H461

Formula: C63H99D8N11O29

Molecular Weight: 1490.63

Purity: >90% (HPLC)

Storage & Shipping

Shipping requirement: Dry Ice

Storage conditions: -20°C

Dry ice required. Additional fees may apply. For more details, visit our shipping page.

Other Names

Frizzled-8; FZD8; APF-d8; Antiproliferative Factor (d8 isotope-labeled synthetic Glycopeptide)

For research and development use only

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