GA121000: Fmoc-Ser(GalNAc(Ac)3-α-D)-OH

GA121000

Fmoc-Ser(GalNAc(Ac)3-α-D)-OH

An Fmoc-protected L-serine building block carrying an α-D-GalNAc residue, designed for solid-phase peptide synthesis (SPPS) of glycopeptides. The Nα-Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free α-carboxylic acid is available for coupling to the growing resin-bound peptide. The sugar hydroxyl groups are protected as three acetate esters (Ac3), which keep the glycan inert during synthesis and are removed under mild base (e.g., sodium methoxide / hydrazine) after assembly. The installed glycan is the Tn antigen (GalNAcα-O-Ser/Thr), the simplest mucin-type O-glycan and a tumor-associated carbohydrate antigen, widely used to build glycopeptides for cancer vaccine, anti-Tn antibody, and lectin (e.g., MGL/CLEC10A) research.

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GA121000: Fmoc-Ser(GalNAc(Ac)3-α-D)-OH
  • GA121000: Fmoc-Ser(GalNAc(Ac)3-α-D)-OH
  • GA121000: Fmoc-Ser(GalNAc(Ac)3-α-D)-OH
Pack Size
Quantity
Price
25 mg GA121000-25MG + $125.00 fee for orders under $500.00 $300.00 USD
$300.00 USD + $125.00 fee for orders under $500.00
100 mg GA121000-100MG $700.00 USD
$700.00 USD
250 mg GA121000-250MG $1,500.00 USD
$1,500.00 USD
500 mg GA121000-500MG $2,750.00 USD
$2,750.00 USD

Technical Data

CAS #: 120173-57-1

Formula: C32H36N2O13

Molecular Weight: 656.63

Purity: >95% (HPLC)

Storage & Shipping

Shipping requirement: Ambient

Storage conditions: -20°C

Other Names

Tn Epitope (Serine); Tn Antigen (Serine, Fmoc, Peracetylated); Fmoc-L-Ser(GalNAc(Ac)3-α-D)-OH; Fmoc-Ser(α-D-GalNAc(Ac)3)-OH; N-α-Fmoc-O-β-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-Serine; N-(9-fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl)-L-Serine; Fmoc-Ser(α-D-GalNAc(Ac)3)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(α-D-GalNAc)-OH, Peracetate

For research and development use only

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