A Blood Group A trisaccharide (GalNAcα1-3[Fucα1-2]Gal) ligand equipped with a biotin tag. The biotin moiety binds with high affinity to streptavidin and neutravidin, enabling straightforward immobilization on chips, in wells, or on other streptavidin/neutravidin-coated platforms. This compound presents the Blood Group A trisaccharide (GalNAcα1-3[Fucα1-2]Gal), a histo-blood group antigen. It is a ligand for anti-A antibodies and A-antigen-recognizing lectins and a probe for blood group typing and host-pathogen interaction studies.