AG924010
β-D-LacNAc-Ethyl-Azide
A β-D-N-acetyllactosamine (LacNAc) ligand equipped with an azide-functionalized linker through a short ethyl spacer. The terminal azide can be covalently coupled to alkyne partners via copper-catalyzed azide-alkyne cycloaddition (CuAAC), or to dibenzocyclooctyne (DBCO) and related strained alkynes using copper-free click chemistry, forming stable 1,2,3-triazole linkages. This compound provides an N-acetyllactosamine (LacNAc; Galβ1-4GlcNAc) building block, a core disaccharide of N- and O-glycans and a ligand for galectins. It is a substrate for sialyltransferases and fucosyltransferases, enabling enzymatic extension to sialylated and fucosylated structures such as sialyl-LacNAc and Lewis antigens.