A β-D-glucose ligand equipped with a terminal alkyne through a hydrophilic PEG3 spacer. The alkyne couples to azide-functionalized partners via copper-catalyzed azide-alkyne cycloaddition (CuAAC), forming stable 1,2,3-triazole linkages. This compound provides a β-D-glucose building block for glycoconjugate synthesis, glycomimetic research, and the construction of probes for glucose-recognizing proteins and lectins.