GP100095

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RPB1 CTD(1615-1621-Lys)-Tn(1619)

DNA-directed RNA polymerase II (Pol II) subunit RPB1 contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr-Ser-Pro-Thr-Ser-Pro-Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process Pol II transcripts.


Sequence:


YSPTS*PSK-NH2
H-Tyr-Ser-Pro-Thr-Ser*-Pro-Ser-Lys-NH2
where S* = Ser* = GalNAcα-O-Ser
1 1

RPB1 CTD(1615-1621-Lys)-Tn(1619)

DNA-directed RNA polymerase II (Pol II) subunit RPB1 contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr-Ser-Pro-Thr-Ser-Pro-Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process Pol II transcripts.


Sequence:

YSPTS*PSK-NH2
H-Tyr-Ser-Pro-Thr-Ser*-Pro-Ser-Lys-NH2
where S* = Ser* = GalNAcα-O-Ser

1 1
1 1
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$375.00 USD
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For research and development use only. Not for human or veterinary use.
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  • Other Names

    RNA polymerase B at C-terminal domain(CTD); RPB1 CTD(Tn) glycopeptide

  • Technical Data

    UniProt ID: P24928

    Formula: C46H73N11O18

    Molecular Weight: 1068.1

    Purity: >90% (HPLC)

  • Storage & Shipping

    Shipping requirement: Ambient

    Storage conditions: -20°C

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