GA631005

Fmoc-Thr(α-D-Man(Ac)4-(1-2)α-D-Man(Ac)3)-OH

An Fmoc-protected L-threonine building block carrying a Manα1-2Manα disaccharide, designed for solid-phase peptide synthesis (SPPS) of glycopeptides. The Nα-Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free α-carboxylic acid is available for coupling to the growing resin-bound peptide. The sugar hydroxyl groups are protected as acetate esters (peracetate), which keep the glycan inert during synthesis and are removed under mild base (e.g., sodium methoxide / hydrazine) after assembly. The installed glycan is the O-mannose disaccharide Manα1-2Man, an extension of protein O-mannosylation, used to build O-mannosyl glycopeptides relevant to α-dystroglycan biology.

Need a quote?

Add a pack size to your cart and click "Get an Instant Quote (.pdf)" on the cart page!

GA631005: Fmoc-Thr(α-D-Man(Ac)4-(1-2)α-D-Man(Ac)3)-OH
Pack Size
Quantity
Price
Actions
25 mg GA631005-25MG $750.00 USD
$750.00 USD
50 mg GA631005-50MG $1,125.00 USD
$1,125.00 USD
100 mg GA631005-100MG $1,975.00 USD
$1,975.00 USD

Technical Data

CAS #: N/A

Formula: C45H53NO22

Molecular Weight: 959.9

Purity: >95% (HPLC)

Storage & Shipping

Shipping requirement: Ambient

Storage conditions: -20°C

Other Names

Fmoc-Thr(Manα(1-2)Man)-OH (Peracetate); Fmoc-Thr(α(1-2)Mannobiose)-OH (Peracetate); N-α-Fmoc-O-(hepta-O-acetyl-α-D-mannopyranosyl-α(1-2)-D-mannopyranosyl)-L-threonine; Fmoc-Thr(Man(Ac)4α(1-2)Man(Ac)3)-OH

For research and development use only

Browse related products

Fmoc Protected Glycoamino Acids for Glycopeptide Synthesis
GA131010: Fmoc-Thr(Galβ(1-3)GalNAc)-OH (Peracetate)

Fmoc Protected Glycoamino Acids for Glycopeptide Synthesis

Threonine Glycoamino Acids
GA130000: H-Thr(α-D-GalNAc)-OH

Threonine Glycoamino Acids