GA131010

Fmoc-Thr(Galβ(1-3)GalNAc)-OH (Peracetate)

An Fmoc-protected L-threonine building block carrying a Galβ1-3GalNAcα disaccharide, designed for solid-phase peptide synthesis (SPPS) of glycopeptides. The Nα-Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free α-carboxylic acid is available for coupling to the growing resin-bound peptide. The sugar hydroxyl groups are protected as acetate esters (peracetate), which keep the glycan inert during synthesis and are removed under mild base (e.g., sodium methoxide / hydrazine) after assembly. The installed glycan is the T antigen / core 1 structure (Galβ1-3GalNAcα-O-Ser/Thr), a tumor-associated carbohydrate antigen and ligand for galectins and the macrophage galactose lectin, used to build glycopeptides for cancer immunology and O-glycobiology research.
Pack Size
$750.00 USD
Sale price  $750.00 USD Regular price 

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GA131010: Fmoc-Thr(Galβ(1-3)GalNAc)-OH (Peracetate)
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Technical Data

CAS #: 125760-33-0

Formula: C45H54N2O21

Molecular Weight: 958.91

Purity: >95% (HPLC)

Storage & Shipping

Shipping requirement: Ambient

Storage conditions: -20°C

Other Names

TF Epitope (Threonine); T Antigen (Threonine,Fmoc, Peracetylated); Thomsen–Friedenreich Antigen; Core 1 Glycan (Threonine); Fmoc-Thr[β-D-Gal(Ac)4-(1-3)-α-D-GalNAc(Ac)2]-OH; O-{2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-4,6-di-O-acetyl-2-deoxy-α-D-galactopyranosyl}-N α-(fluoren-9-yl-methoxycarbonyl)-L-Threonine; Fmoc-Thr(α-Gal β(1-3)GalNAc)-OH, Peracetate

For research and development use only

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