Man5GlcNAc2Asn N-linked Ligands
Man5GlcNAc2Asn (N-linked glycans) can be used to target therapeutics to macrophages or dendritic cells, by exploiting the mannose receptor (CD206). Therapeutic payloads can be directly conjugated to Man ligands or encapsulated in nanoparticles decorated with Man5GlcNAc2Asn ligands.
We provide Man5GlcNAc2Asn ligands with various functional linkers depending on their intended use.