Galα Ligands

Galactose (Galα) ligands can be used to target drugs to hepatocytes in the liver, by exploiting the asialoglycoprotein receptor (ASGPR). ASGPR has a high affinity for Gal-containing ligands. Therapeutic payloads can be directly conjugated to Gal ligands or encapsulated in nanoparticles decorated with Gal ligands.

We provide Galα ligands with various functional linkers depending on their intended use.