Collection: Galα

Galα ligands are a class of molecules that exhibit a high affinity for galactose-binding proteins, such as the asialoglycoprotein receptor (ASGPR), predominantly found on hepatocytes. These ligands play a crucial role in targeted drug delivery systems, where they are used to enhance the uptake of therapeutic agents by specific cells expressing the target receptor, thereby improving drug efficacy and reducing off-target effects. Additionally, Galα ligands are valuable in studying cellular processes and receptor-mediated endocytosis, providing insights into the dynamics of receptor-ligand interactions and intracellular trafficking. Their versatility and specificity make them promising candidates for the development of targeted therapeutics and tools in biomedical research.

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