GP100130

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Biotin-PDPN(74-85-Gly-Lys)-Tn(77) Mouse

PDPN (UniProt ID Q62011) synthetic Glyco-dodecapeptide epitope (Glu74-Ser85-Gly-Lys) that is present within the extracellular domain of the glycoprotein podoplanin. The glycopeptide fragment has tumor-associated cancer antigen Tn at Thr77. Biotin was appended on the ε-amine of the C-terminal lysine. The posttranslational GalNAc modification is expressed by an aggressive fibrosarcoma, Ag104A, and is bound by Anti-Tn Antigen [237mAb].


Sequence:


ERGT*KPPLEELS-GK(biotinyl)-NH2
H-Glu-Arg-Gly-Thr*-Lys-Pro-Pro-Leu-Glu-Glu-Leu-Ser-Gly-Lys(biotin)NH2
where T* = Thr* = GalNAcα-O-Thr
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Biotin-PDPN(74-85-Gly-Lys)-Tn(77) Mouse

PDPN (UniProt ID Q62011) synthetic Glyco-dodecapeptide epitope (Glu74-Ser85-Gly-Lys) that is present within the extracellular domain of the glycoprotein podoplanin. The glycopeptide fragment has tumor-associated cancer antigen Tn at Thr77. Biotin was appended on the ε-amine of the C-terminal lysine. The posttranslational GalNAc modification is expressed by an aggressive fibrosarcoma, Ag104A, and is bound by Anti-Tn Antigen [237mAb].


Sequence:

ERGT*KPPLEELS-GK(biotinyl)-NH2
H-Glu-Arg-Gly-Thr*-Lys-Pro-Pro-Leu-Glu-Glu-Leu-Ser-Gly-Lys(biotin)NH2
where T* = Thr* = GalNAcα-O-Thr

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  • Other Names

    Synthetic podoplain glycopeptide; PDPN(Tn) glycopeptide

  • Technical Data

    UniProt ID: Q62011

    Formula: C84H141N23O29S

    Molecular Weight: 1969.2

    Purity: >90% (HPLC)

  • Storage & Shipping

    Shipping requirement: Dry Ice

    Storage conditions: -20°C

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