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α-Man-6-phosphate-PEG3-Alkyne

α-Man-6-phosphate-PEG3-Alkyne molecular structure

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Product Details

Name α-Man-6-phosphate-PEG3-Alkyne
Product No.PE631010
Synonym(s) α-M6P-PEG3-Propyne; (Dodec-11-yn-3,6,9-trioxadodecyl) α-D-mannose-6-phosphate; 2-{2-[2-(Prop-2-ynyloxy)ethoxy]ethoxy}ethyl mannose-6-phosphate
CategoryCarbohydrate LinkersPEGylatedAlkynes
FormulaC15H27O12P
Molecular Weight430.34
AvailabilityYes
Availability in BulkYes
DescriptionMannose-6-phosphate (M6P) glycan is a crucial signal for the trafficking of lysosomal enzymes to lysosomes and is recognized by M6P receptors (MPRs). The resulting enzyme-MPR complex is delivered to early endosomes. Development of therapeutic enzymes for lysosomal storage diseases require M6P glycans for cellular uptake and lysosomal targeting.
CommentsM6P; PEG3; Alkyne; Mannose-6-phosphate
Datasheet(s)PE631010_COA.pdf (89.52 KB)
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