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HSV-1 gB: Biotinyl-GPAT(STn)PAP-NH₂, where STn = Neu5Acα(2-6)GalNAc

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SKUPack SizeAvailabilityPriceQuantity
GP000035-0.25MG0.25mgIn StockUS$500.00
GP000035-0.5MG0.5mgIn StockUS$750.00
GP000035-1MG1mgIn StockUS$1,250.00

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Product Details

Name HSV-1 gB: Biotinyl-GPAT(STn)PAP-NH₂, where STn = Neu5Acα(2-6)GalNAc
Product No.GP000035
Synonym(s) Biotinylated HSV-1 Envelope glycoprotein B synthetic fragment 50-56 (STn glycosylation at Thr-53); Biotinyl-GPAT(Neu5Acα2,6GalNAc)PAP-NH₂
CategoryGlycopeptidesO-Linked
FormulaC56H88N12O23S
Molecular Weight1329.4
AvailabilityYes
Availability in BulkYes
Purity>90%
DescriptionHerpes simplex virus-1 (HSV-1 or HHV-1) Glycoprotein B (gB) glycopeptide fragment (50-56) is an envelope protein that is essential for viral growth. Before entering host cells, HSV-1 uses this glycopeptide ligand to bind paired immunoglobulin-like type 2 receptor α (PILRα) on immune cells. PILRα belongs to the Siglec (sialic acid-binding immunoglobulin-like lectin)-like family, members of which bind sialic acid ligands.
CommentsN-Acetyl-D-Galactosamine; O-Linked; Mono-Glycosylated; L-Threonine; C-Terminus-Amide; STn-Glycopeptide
ReferencesKuroki, K. et al., Proc Natl Acad Sci. USA 2014, 111, 8877–8882.
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