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Podoplanin Fragment: H-ERGT(GalNAc)KPPLEELSGK(biotinyl)-NH₂


SKUPack SizeAvailabilityPriceQuantity
GP100130-0.5MG0.5mgIn StockUS$375.00
GP100130-1MG1mgIn StockUS$600.00

Product Details

Name Podoplanin Fragment: H-ERGT(GalNAc)KPPLEELSGK(biotinyl)-NH₂
Product No.GP100130
Synonym(s) PDPN(74-85)-Tn(77) Mouse; Synthetic tumor-specific glyco-dodecapeptide fragment of Podoplanin, a small membrane mucin-type glycoprotein containing the Tn antigen, is a target of 237mAb Fab antibody.
Molecular Weight1969.2
Availability in BulkYes
DescriptionThe structure of the antigen binding fragment (Fab) for 237mAb, a glycan-specific anti-Tn antibody, was determined using the dodecameric GalNAc-peptide fragment, ERGT(GalNAc)KPPPLEELS, a segment of a tumor-associated Podoplanin glycoprotein. 237mAb, an IgG2a κ, was the first glycan-specific anti-Tn antibody to be solved.
CommentsN-Acetyl-D-Galactosamine; O-Linked; Mono-Glycosylated; L-Threonine; C-Terminus-Amide
ReferencesCory L. Brooks, et al., Proc Natl Acad Sci USA. 2010; 107: 10056–10061.
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