NEW!!! Many of our products can now be purchased online! Please browse the product pages for more information.
For custom quotations/inquiries, contact us through the online form or by emailing info@sussex-research.com. Thank you for your patience as we continue to update our website!

Cart

IgA1 Hinge Peptide: HYTNPSQDVTVPCPVPSTPPTPS(α-GalNAc)PSTPPTPSPSCCHPR-NH₂

Purchase

SKUPack SizeAvailabilityPriceQuantity
GP100050-0.5MG0.5mgIn StockUS$375.00
GP100050-1MG1mgIn StockUS$575.00
GP100050-2MG2mgIn StockUS$975.00
Inquire

Product Details

Name IgA1 Hinge Peptide: HYTNPSQDVTVPCPVPSTPPTPS(α-GalNAc)PSTPPTPSPSCCHPR-NH₂
Product No.GP100050
Synonym(s) IgA1 HP(208-245)-Ser230(Tn)
CategoryGlycopeptidesO-Linked
FormulaC179H275N49O60S3
Molecular Weight4169.59
AvailabilityYes
Availability in BulkYes
Purity>90%
DescriptionImmunoglobulin A (IgA1) tryptic peptide: Hinge Region glycopeptide fragment Hys208-Arg245 with GalNAc (Tn) glycosylation at Ser230. Immunoglobulin A (IgA) is the most abundantly produced antibody with an important role in mucosal immunity. Occurring in two structurally and functionally distinctive subclasses (IgA1 and IgA2), aberrant O-glycosylation in the hinge region of IgA1 plays a key role in the pathogenesis of IgA nephropathy (IgAN).
CommentsN-Acetyl-D-Galactosamine; O-Linked; Mono-Glycosylated; L-Serine; C-Terminus-Amide
ReferencesV. Franc et al., J Proteomics 2013, 92, 299–312.
‹ Back to Catalogue