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IgA1 Hinge Peptide: VPSTPPT(α-GalNAc)PS(α-GalNAc)PS(α-GalNAc)TPPTPSPS-NH₂

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SKUPack SizeAvailabilityPriceQuantity
GP100040-0.25MG0.25mgIn StockUS$475.00
GP100040-0.5MG0.5mgIn StockUS$675.00
GP100040-1MG1mgIn StockUS$975.00

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Product Details

Name IgA1 Hinge Peptide: VPSTPPT(α-GalNAc)PS(α-GalNAc)PS(α-GalNAc)TPPTPSPS-NH₂
Product No.GP100040
Synonym(s) HP(222-240)-Tn(228,230,232)
CategoryGlycopeptidesO-Linked
FormulaC105H167N23O43
Molecular Weight2439.58
AvailabilityYes
Availability in BulkYes
Purity>90%
DescriptionThe hinge region (HR) of IgA1 contains two octapeptide repeats with multiple Pro, Ser, and Thr residues and 3 to 6 O-glycan chains consisting of N-acetylgalactosamine (GalNAc) that may also carry galactose (Gal) and/or sialic acid (Neu5Ac). Abnormal HR glycosylation results in IgA nephropathy (IgAN), the most common primary glomerulonephritis and an important cause of end-stage renal disease.
CommentsN-Acetyl-D-Galactosamine; O-Linked; Tri-Glycosylated; L-Threonine; C-Terminus-Amide; GP120170
Datasheet(s)GP100040_COA.pdf (80.987 KB)
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