Name |
HSV-1 gB: Biotinyl-GPAT(STn)PAP-NH₂, where STn = Neu5Acα(2-6)GalNAc
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Product No. | GP000035 |
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Synonym(s) |
Biotinylated HSV-1 Envelope glycoprotein B synthetic fragment 50-56 (STn glycosylation at Thr-53); Biotinyl-GPAT(Neu5Acα2,6GalNAc)PAP-NH₂
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Category | GlycopeptidesO-Linked |
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Formula | C56H88N12O23S
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Molecular Weight | 1329.4 |
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Availability | Yes |
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Availability in Bulk | Yes |
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Purity | >90% |
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Description | Herpes simplex virus-1 (HSV-1 or HHV-1) Glycoprotein B (gB) glycopeptide fragment (50-56) is an envelope protein that is essential for viral growth. Before entering host cells, HSV-1 uses this glycopeptide ligand to bind paired immunoglobulin-like type 2 receptor α (PILRα) on immune cells. PILRα belongs to the Siglec (sialic acid-binding immunoglobulin-like lectin)-like family, members of which bind sialic acid ligands. |
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Comments | N-Acetyl-D-Galactosamine; O-Linked; Mono-Glycosylated; L-Threonine; C-Terminus-Amide; STn-Glycopeptide |
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References | Kuroki, K. et al., Proc Natl Acad Sci. USA 2014, 111, 8877–8882. |
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