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Core 2 O-Glycan (Threonine, Fmoc, Peracetylated)

Core 2 O-Glycan (Threonine, Fmoc, Peracetylated) molecular structure


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Product Details

Name Core 2 O-Glycan (Threonine, Fmoc, Peracetylated)
Product No.GA131030
Synonym(s) Fmoc-Thr(GlcNAc(Ac)₃-β(1-6)(Gal(Ac)₄-β(1-3)GalNAc(Ac))-OH; Fmoc-Thr(GlcNAc-β(1-6)(Gal β (1-3)GalNAc)-OH, Peracetate
CategoryGlycoamino AcidsThreonine
Molecular Weight1246.18
AvailabilityNo - Please inquire for availability information
Availability in BulkYes
Purity>95% (HPLC)
DescriptionCore Glycan: Core 2 glycan is one of 4 core structures of O-GalNAc glycans of mucins. The Core 2 glycan structure is an extension of Core 3 by N-acetylglucosamine β1,6 branching and is catalyzed by three different core2 β1,6-N-acetylglucosaminyltransferase-1–3 (C2GnT-1–3).. Changes in levels of any one of these transferases may indicate celular malignancy.
CommentsN-Acetyl-D-Galactosamine; O-Link; Trisaccharide; Threonine; Blocked; Amino Acid; Ac
ReferencesLee S.H., et al., J. Biol. Chem. 2010, 285, 37683-37692.
Datasheet(s)GA131030_COA.pdf (54.56 KB)
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