NEW!!! Many of our products can now be purchased online! Please browse the product pages for more information.
For custom quotations/inquiries, contact us through the online form or by emailing Thank you for your patience as we continue to update our website!

STF Antigen (Threonine, Fmoc, Methyl Ester, Peracetylated)

STF Antigen (Threonine, Fmoc, Methyl Ester, Peracetylated) molecular structure


SKUPack SizeAvailabilityPriceQuantity
GA131020-25MG25mgIn StockUS$5,000.00
GA131020-50MG50mgIn StockUS$7,500.00
GA131020-100MG100mgIn StockUS$12,750.00
GA131020-250MG250mgIn StockInquire

Please note, this product has a special shipping requirement that will apply an additional fee in your cart: Dry Ice


Product Details

Name STF Antigen (Threonine, Fmoc, Methyl Ester, Peracetylated)
Product No.GA131020
Synonym(s) Fmoc-Thr(Neu5Acα2-3Galβ1-3GalNAc)-OH (peracetylated, methyl ester); ST Antigen (Fmoc-Threonine, Peracetate, Methyl ester); α(2,3)Sialyl TF Antigen (Fmoc-Threonine, Peracetate, Methyl ester); Neu5Acα(2,3)Galβ(1,3)GalNAcα–Thr (Fmoc, Peracetate, Methyl ester); Nα-(Fluoren-9-ylmethoxycarbonyl)-O-[(methyl 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonate)-(2→3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1→3)-2-N-acetamido-2-deoxy-4,6-di-O-acetyl-α-D-]-L-threonine
CategoryGlycoamino AcidsThreonine
CAS No.125760-33-0
Molecular Weight1390.3
Availability in BulkYes
Purity>90% (HPLC)
DescriptionTumor-Associated Carbohydrate Antigen (TACA). STF-antigen (also ST) is a sialylated form of the truncated O-glycosylated core determinant TF (also T) with structure: Neu5Acα2-3Galβ1-3GalNAcα-O-Ser/Thr. STF results from an early sialylation of the TF antigen due to overexpression of the enzyme α2,3sialylT and/or disruption of further glycan elongation processes. STF is negligibly expressed in healthy tissues but overexpressed in human carcinomas . As such, STF is implicated in tumour cell organotropic metastasis. Targeting immune responses to truncated variants of O-glycan chains expressed by tumour cells represents a promising approach for the development of antigen-specific therapeutic vaccines against cancers, and accumulated evidence has rendered STF a prime target for cancer immunotherapy.
CommentsN-Acetyl-D-Galactosamine; O-Link; Trisaccharide; Threonine; Blocked; Amino Acid; Ac; Me
Datasheet(s)GA131020_COA.pdf (89.684 KB)
‹ Back to Catalogue