(β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
Other Names:
Tris-GalNAc-β-Ala-PEG3-N3;
(β-D-GalNAc)3-β-Ala-PEG3-N3;
Tris-β-GalNAc-β-Alanine-PEG3-azide;
Triantennary-β-GalNAc-β-Alanine-PEG3-azide