TP53(140-156)-GlcNAc(149)

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Product #: GP200030

TP53(140-156)-GlcNAc(149)

Product Details

Sequence TCPVQLWVDS*TPPPGTR-NH2;
Thr-Cys-Pro-Val-Gln-Leu-Trp-Val-Asp-Ser*-Thr-Pro-Pro-Pro-Gly-Thr-Arg-NH2;
where S* = Ser* = GlcNAcβ-O-Ser
Other Names Cellula tumor P53, TP53(GlcNAc) glycopeptide
UniProt IDP04637
FormulaC90H142N24O29S
Molecular Weight2056.3
Purity>90%
DescriptionSynthetic P53 glycopeptide 17 AA fragment (Thr140-Arg156) with posttranslational medication (GlcNAc) at Ser149. O-GlcNAcylation at Ser 149 stabilizes p53 by blocking ubiquitin-dependent proteolysis. Won Cho et al. Nature Cell Biology 2006, 8, 1074–1083. C-terminus is an amide.
Keywords TP53(140-156)-GlcNAc(149), N-Acetyl-D-Glucosamine, O-Linked, Mono-Glycosylated, L-Serine, C-Terminus-Amide, GlcNAc-Glycopeptide, Formerly GP221050, Cellula tumor P53, TP53(GlcNAc) glycopeptide, C90H142N24O29S
Shipping RequirementDry Ice
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