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TP53(140-156)-GlcNAc(149)

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SKU: 260a94040ad4 Categories: ,

Product #: GP200030

TP53(140-156)-GlcNAc(149)

Product Details

Sequence TCPVQLWVDS*TPPPGTR-NH2;
H-Thr-Cys-Pro-Val-Gln-Leu-Trp-Val-Asp-Ser*-Thr-Pro-Pro-Pro-Gly-Thr-Arg-NH2;
where S* = Ser* = GlcNAcβ-O-Ser
Other Names Cellula tumor P53, TP53(GlcNAc) glycopeptide
UniProt ID P04637
Formula C90H142N24O29S
Molecular Weight 2056.3
Purity >90% (HPLC)
Description Synthetic P53 glycopeptide 17 AA fragment (Thr140-Arg156) with posttranslational medication (GlcNAc) at Ser149. O-GlcNAcylation at Ser 149 stabilizes p53 by blocking ubiquitin-dependent proteolysis. C-terminus is an amide.
Keywords TP53(140-156)-GlcNAc(149), N-Acetyl-D-Glucosamine, O-Linked, Mono-Glycosylated, L-Serine, C-Terminus-Amide, GlcNAc-Glycopeptide, Formerly GP221050, Cellula tumor P53, TP53(GlcNAc) glycopeptide, C90H142N24O29S
References Won Cho et al. Nature Cell Biology 2006, 8, 1074–1083
Shipping Requirement Dry Ice
Safety Data Sheets Email info@sussex-research.com