Pack SizePrice (USD)AvailabilityQuantity
25mg$700.00In Stock
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100mg$1,850.00In Stock
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250mg$3,750.00In Stock
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500mg$6,000.00In Stock
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Tf Antigen: Fmoc-Ser(Galβ(1-3)GalNAc)-OH (Peracetate)

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SKU: 931d2b4cc6d2 Categories: ,

Product #: GA121010

Tf Antigen: Fmoc-Ser(Galβ(1-3)GalNAc)-OH (Peracetate)

Product Details

Other Names Tf Epitope (Serine), T Antigen (Serine,Fmoc, Peracetylated), Thomsen–Friedenreich Antigen, Core 1 Glycan (Serine), Fmoc-L-Ser(Galβ(1-3)GalNAc)-OH (Peracetate), Fmoc-Ser[β-Gal(Ac)4-(1-3)-α-GalNAc(Ac)2]-OH, O-{2-N-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-4,6-di-O-acetyl-2-deoxy-α-D-galactopyranosyl}-N α-(fluoren-9-yl-methoxycarbonyl)-L-Serine
CAS #125760-30-7
FormulaC44H52N2O21
Molecular Weight944.88
Purity>95% (HPLC)
DescriptionTumor-Associated Carbohydrate Antigen (TACA). TF is a truncated O-glycosylated core determinant (Core 1) with structure: Galβ1-3GalNAcα-O-Ser/Thr. In normal Mamalian cells, the TF determinant is masked by larger glycan residues. Once unmasked, TF serves as an important recognition element, mediating several cell-cell interactions. As such, TF is implicated in tumour cell organotropic metastasis. Targeting immune responses to truncated variants of O-glycan chains expressed by tumour cells represents a promising approach for the development of antigen-specific therapeutic vaccines against cancers, and accumulated evidence has rendered TF a potential target for cancer immunotherapy.
Keywords Tf Antigen: Fmoc-Ser(Galbeta(1-3)GalNAc)-OH (Peracetate), N-Acetyl-D-Galactosamine, O-Link, Disaccharide, Serine, Blocked, Amino Acid, Ac, Tf Epitope (Serine), T Antigen (Serine,Fmoc, Peracetylated), Thomsen–Friedenreich Antigen, Core 1 Glycan (Serine), Fmoc-L-Ser(Galbeta(1-3)GalNAc)-OH (Peracetate), Fmoc-Ser[beta-Gal(Ac)4-(1-3)-alpha-GalNAc(Ac)2]-OH, O-{2-N-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-4,6-di-O-acetyl-2-deoxy-alpha-D-galactopyranosyl}-N alpha-(fluoren-9-yl-methoxycarbonyl)-L-Serine, C44H52N2O21, glycoamino acid, glycoamino acids, glyco amino acid, glycocosylated amino acids
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