Category: STn Glycan

NeuAcα(2-6)GalNAc-α-PEG3-Acid

Sialyl-Tn (STn) glycan ligand of the STn Antigen. Amine reactive. Neu5Acα2-6GalNAc is equipped with a triethylene glycol (PEG3), carboxyl-functionalized (amine-reactive) linker/spacer. The truncated glycan is found on the Sialyl-Tn antigen (STn) where it is linked to a serine (Ser) or threonine (Thr) as Neu5Acα2-6GalNAcα-O-Ser/Thr and considered an aberrant tumour-associated carbohydrate antigen (TACA).

Other Names: 6'-Sialyl GalNAc-PEG3-COOH; NeuAcα(2-6)GalNAc-α-PEG3-COOH; Neu5Acα(2-6)GalNAc-α-PEG3-COOH; 6'-Sialyl N-acetyl-D-galactosamine-PEG3-COOH; 6'-Sialyl N-acetylgalactosamine-PEG3-COOH; 2-[2-(2-Carboxyethoxy)ethoxy]ethyl 2-acetamido-6-O-(5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosylonic acid)-2-deoxy-β-D-galactopyranoside; (8-Carboxy-3,6-dioxaoctyl) 2-acetamido-6-O-(5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosylonic acid)-2-deoxy-β-D-galactopyranoside; tumor associated carbohydrate antigen (TACA)