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0.5mg$375.00In Stock
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RPB1 CTD(1615-1621-Lys)-Tn(1619)

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Product #: GP100095

RPB1 CTD(1615-1621-Lys)-Tn(1619)

Product Details

Sequence YSPTS*PSK-NH2;
Tyr-Ser-Pro-Thr-Ser*-Pro-Ser-Lys-NH2;
where S* = Ser* = GalNAcα-O-Ser
Other Names RNA polymerase B at C-terminal domain(CTD), RPB1 CTD(Tn) glycopeptide
UniProt IDP24928
FormulaC46H73N11O18
Molecular Weight1068.1
Purity>90%
DescriptionDNA-directed RNA polymerase II (Pol II) subunit RPB1 contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr-Ser-Pro-Thr-Ser-Pro-Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process Pol II transcripts.
Keywords RPB1 CTD(1615-1621-Lys)-Tn(1619), N-Acetyl-D-Galactosamine, O-Linked, Mono-Glycosylated, L-Serine, C-Terminus-Amide, Tn-Glycopeptide, Formerly GP121010, RNA polymerase B at C-terminal domain(CTD), RPB1 CTD(Tn) glycopeptide, C46H73N11O18
Shipping RequirementAmbient
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