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MUC5AC(2449-2464)-Tn(2460)

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Product #: GP100084

MUC5AC(2449-2464)-Tn(2460)

Product Details

Sequence GTTPSPVPTTST*TSAP-NH2;
H-Gly-Thr-Thr-Pro-Ser-Pro-Val-Pro-Thr-Thr-Ser-Thr*-Thr-Ser-Ala-Pro-NH2;
where T* = Thr* = GalNAcα-O-Thr
Other Names Mucin5, Synthetic MUC-5 (Tn) glycopeptide, MUC5AC-Tn(3), MUC5AC-3, MUC5AC(2449-2464)-Tn(2460)
UniProt ID P98088
Formula C71H118N18O30
Molecular Weight 1703.8
Purity >90% (HPLC)
Description Synthetic, glycopepMuc5AC (UniProt ID P98088) is a gel-forming glycoprotein produced by the goblet cells in the tracheobronchial surface epithelium. MUC5AC-Tn(12) is a synthetic 16 amino acid glycopeptide fragment and tandem repeat sequence of MUC5AC (Gly2449-Pro2464) where O-glycosylation (GalNAc) is at amino acid Thr-12 (Thr2460 in protein). The C- terminus is an amide.tide Mucin-5 peptide fragment from Gly4221 to Ala4235. Pro was added on C-terminal to make an analogue of MUC-5 (16 AA in total). The MUC5AC gene, which is mainly expressed in gastric and respiratory mucosae, exhibits 8 amino acid tandemly repeated domain, TTSTTSAP.4 O-glycosylation α-GalNAc is at position Thr4232. The C- terminus is amide.
Keywords MUC5AC(2449-2464)-Tn(2460), N-Acetyl-D-Galactosamine, O-Linked, Mono-Glycosylated, L-Threonine, C-Terminus-Amide, Tn-Glycopeptide, Mucin5, Synthetic MUC-5 (Tn) glycopeptide, MUC5AC-Tn(3), C71H118N18O30
Shipping Requirement Dry Ice
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