Pack Size Price (USD) Availability Quantity
25mg$940.00In Stock
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50mg$1,400.00In Stock
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100mg$1,950.00In Stock
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250mg$3,500.00In Stock
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Core 3 O-Glycan: Fmoc-Thr(GlcNAcβ(1-3)GalNAc)-OH (Peracetate)


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SKU: f67bf54d1bcc Categories: ,

Product #: GA131025

Core 3 O-Glycan: Fmoc-Thr(GlcNAcβ(1-3)GalNAc)-OH (Peracetate)

Product Details

Other Names Core 3 O-Glycan on Threonine, Fmoc-Thr(β-D-GlcNAc(Ac)3-(1-3)-α-D-GalNAc(Ac)2)-OH
Formula C45H55N3O20
Molecular Weight 957.93
Purity >95% (HPLC)
Description Core Glycan: Core 3 glycan is one of 4 core structures of O-GalNAc glycans of mucins. Core 3 β1,3-N-acetylglucosaminyltransferase (C3GnT) controls the biosynthesis of core 3 O-glycans and is expressed mainly in the intestine and salivary glands. Core 3 disaccharide can be further extended to form larger glycans. Reduced core3 synthase activity has been detected in malignant tumor cells and it has been reported that increased core3 O-glycan structure negatively regulates tumorigenesis by regulating the function of α2β1 integrin in prostate cancer.
Keywords Core 3 O-Glycan: Fmoc-Thr(GlcNAcbeta(1-3)GalNAc)-OH (Peracetate), N-Acetyl-D-Galactosamine, O-Link, Disaccharide, Threonine, Blocked, Amino Acid, Ac, Core 3 O-Glycan on Threonine, Fmoc-Thr(beta-D-GlcNAc(Ac)3-(1-3)-alpha-D-GalNAc(Ac)2)-OH, C45H55N3O20, glycoamino acid, glycoamino acids, glyco amino acid, glycocosylated amino acids
References Lee S. H., et al., J. Biol. Chem. 2009, 284, 17157–17169.
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