Amino Acid Analysis

Researchers often require knowledge of the types and concentrations of free amino acids in biological systems to provide insight into the relationships and function of this class of compounds in those systems.

Sussex Research provides quantitative analysis of the 20 naturally occuring proteinogenic amino acids in biological samples via LC-MS/MS. We have established in-house methods for aqueous-based sample matricies and are able to adapt the methods to other matricies as required. The achievable lower limits of quantitation (LLOQ) are in the low ng/mL (ppb) range with LLOQ’s and calibration ranges tailored to specific studies. If desired, the methods may also be modified to include non-proteinogenic amino acids for quantitative or qualitative purposes.