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O-Linked (Mucin type alpha-GalNAc)
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Carbohydrate functionalized linker/spacer systems are useful for protein or surface modification, drug delivery or nanoparticle synthesis. Customized systems may be prepared upon request. Polyethylene glycol (PEG) or alkyl (Cn) linkers. - R = N3, NH2, SH, CO2H
- Synthetic Intermediates - Donors -Glycals
Nitrophenyl oligosaccharides - Customized nitrophenyl glycans may be prepared upon request.
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Sussex products are used to create differentiated products through glycosylation of small molecules, peptides, proteins, oligonucleotides, etc. Incorporation of carbohydrate recognition elements can improve therapeutic properties and a variety of physical properties including stabilization and solubility. Sussex welcomes custom synthesis and will utilise its synthetic expertise to accommodate the specific needs of our collaborative partners. For specific or custom requirements, please contact us at your convenience.
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Glycopeptides (Select from our inventory of prepared glycopeptides or consider a custom synthesis
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N-Linked (GlcNAc)
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O-Linked (Gal, Glc, Man)
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O-Linked (beta-Glucosamine)
Pseudaminic Acid (Pse) is a sialic acid-like saccharide first found in the LPS of Pseudomonas aeruginosa (1984). Also observed in several other organisms including the gastrointestinal pathogens Helicobacter pylori and Campylobacter jejuni. Pse is thought to influence pathogenesis through bacterial adhesion, invasion, and immune evasion.
Synthetic oligosaccharides - Sussex will adapt its oligosaccharide synthesis methodologies to your specific di-, tri, tetra- or larger saccharide or glycosaminoglycan (GAG) oligosaccharide.
Advanced Glycosylation Products & Synthetic Solutions
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Sussex Research
COPYRIGHT 2004-2008 Sussex Research Laboratories Inc. / All rights reserved / www.sussex-research.com
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Discover the therapeutic potential of carbohydrates
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