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Featured Applications

Sussex Research Laboratories Inc. has been working in the carbohydrate field for over two decades and have applied our synthetic strategies to seemingly countless problems. We have enabled application of complex carbohydrate systems for drug discovery, drug delivery, drug targeting, carbohydrate-based vaccine development, immunotherapy, therapeutic enhancement and diagnostic/bio-analytical assay development.

Drug Targeting - GalNAc

Targeted drug delivery of therapeutic payloads using N-acetylgalactosamine (GalNAc) conjugates that bind to Ashwell-Morell Receptors (asialoglycoprotein receptors or ASGPR) found in liver hepatocytes has become a leading delivery approach particularly for therapeutic oligonucleotides.

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Vaccine Development – Polysaccharide Chemistry

Bacteria are highly glycosylated pathogens. Glycoconjugate vaccines have been proven to be a successful strategy to prevent infectious diseases with the global pneumococcal vaccine market estimated to be > $8 billion (USD) in 2021.

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Cancer – Glycans

It is well established that abnormal glycosylation on tumour cells compared to healthy cells is a hallmark of cancer and common to all cancers. Moreover, specific glycans on cell surface proteins actively drive tumour development and progression. New frontiers in drug discovery & development are being realized thanks to discoveries being made in glycobiology.

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Monoclonal Antibody Development – Glycopeptides & Glycoconjugate Antigens

Therapeutic antibodies have become the predominant class of new drugs developed in recent years. Whether it is the antigen required to screen antibodies or to produce an antibody, we have the synthetic tools to produce carbohydrate antigens and their respective carrier protein conjugates.

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  • Sussex Research Laboratories Inc. to Exhibit at the 9th Annual OPT Congress

    Sussex Research Laboratories Inc. to Exhibit at...

    Sussex Research Laboratories Inc. is excited to announce its sponsorship and participation in the upcoming OPT Congress, the leading conference for advancements in oligonucleotides and mRNA therapeutics. Celebrating its 9th...

    Sussex Research Laboratories Inc. to Exhibit at...

    Sussex Research Laboratories Inc. is excited to announce its sponsorship and participation in the upcoming OPT Congress, the leading conference for advancements in oligonucleotides and mRNA therapeutics. Celebrating its 9th...

  • Sussex Research Laboratories Inc. to Exhibit at Society for Glycobiology's annual meeting Hawaii

    Sussex Research Laboratories Inc. to Exhibit at...

    We're thrilled to announce our participation in the upcoming Society for Glycobiology's annual meeting in beautiful Hawaii from November 5th to 8th. We are excited to have our Chief Scientific Officer,...

    Sussex Research Laboratories Inc. to Exhibit at...

    We're thrilled to announce our participation in the upcoming Society for Glycobiology's annual meeting in beautiful Hawaii from November 5th to 8th. We are excited to have our Chief Scientific Officer,...

  • Sussex Research Laboratories Inc. to Exhibit at BPS 2023 in Napa, California

    Sussex Research Laboratories Inc. to Exhibit at...

    Exciting news awaits! Sussex Research Laboratories Inc. is poised to unveil their pioneering strides in pharmaceutical development of peptide therapeutics at the highly anticipated Boulder Peptide Symposium (BPS) 2023, set...

    Sussex Research Laboratories Inc. to Exhibit at...

    Exciting news awaits! Sussex Research Laboratories Inc. is poised to unveil their pioneering strides in pharmaceutical development of peptide therapeutics at the highly anticipated Boulder Peptide Symposium (BPS) 2023, set...

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  • Sussex Research Laboratories Inc. Welcomes Dr. Nycholat as New CSO and Director of U.S. Subsidiary in San Diego

    Sussex Research Laboratories Inc. Welcomes Dr. ...

    Sussex Research Laboratories Inc. (Sussex Research), a global leader in the translation of complex carbohydrate chemistries into unique, leading-edge products and services that enable researchers to explore and exploit glycomics...

    Sussex Research Laboratories Inc. Welcomes Dr. ...

    Sussex Research Laboratories Inc. (Sussex Research), a global leader in the translation of complex carbohydrate chemistries into unique, leading-edge products and services that enable researchers to explore and exploit glycomics...

  • Sussex Research Laboratories Inc. Appoints Dr. Corwin Nycholat to Advisory Board

    Sussex Research Laboratories Inc. Appoints Dr. ...

    Sussex Research Laboratories Inc. (Sussex Research), a global leader in carbohydrate synthesis and the translation of complex carbohydrate chemistries into unique, leading-edge products that enable researchers to explore and exploit...

    Sussex Research Laboratories Inc. Appoints Dr. ...

    Sussex Research Laboratories Inc. (Sussex Research), a global leader in carbohydrate synthesis and the translation of complex carbohydrate chemistries into unique, leading-edge products that enable researchers to explore and exploit...

  • Sussex Research Laboratories Inc. / Queen’s University collaboration receives support to develop novel small molecule therapies for COVID-19

    Sussex Research Laboratories Inc. / Queen’s Uni...

    Sussex Research Laboratories Inc. (Ottawa, Canada) today announced that Queen’s University and the Southeastern Ontario Academic Medical Organization (SEAMO) has awarded grants for two COVID-19 Rapid Response collaborations between Queen’s...

    Sussex Research Laboratories Inc. / Queen’s Uni...

    Sussex Research Laboratories Inc. (Ottawa, Canada) today announced that Queen’s University and the Southeastern Ontario Academic Medical Organization (SEAMO) has awarded grants for two COVID-19 Rapid Response collaborations between Queen’s...

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